Conditions

Retinal diseases lead to visual impairment in millions of patients worldwide. The typical pathological manifestations of Retinal diseases involve the degeneration and demise of photoreceptors and retinal pigment epithelium cells, which lack the capacity for regeneration.

Stem Cells for Retinal diseases

Stem cells have the capacity to enhance the microenvironment of the retina through the secretion of trophic factors and the regulation of the immune response. This, in turn, facilitates vascular repair and promotes the survival of cells.

The advanced phases of retinal detachment are distinguished by significant loss of retinal neurons. Consequently, the direct application of stem cells to replace these damaged neurons is a notable focus of research. Numerous studies have demonstrated that transplanted stem cells into the impaired retina can undergo differentiation into retinal cells, and they may even integrate into the retina, contributing to the restoration of visual function in cases of retinal detachment.